---
title: "Alpha-Lipoic Acid: A Mitochondrial Antioxidant - Limitless Mindset"
description: An antioxident rich chemical, that fights stress and a variety neurodegenerative diseases. A University of Massachusetts study also demonstrated that it increas
author: Jonathan Roseland
url: https://www.limitlessmindset.com/nootropic-ingredients/313-alpha-lipoic-acid
---

![](https://www.limitlessmindset.com/data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)

# Alpha-Lipoic Acid

Ⓒ By **Jonathan Roseland**

Applied Neuroscience Strategist, K-Selected Biohacker, Tantric husband, Promethean peaceful parent, Adventuring philosopher, Raconteur, and Author. He spent +14 years researching the intersection of human performance enhancement and advanced personal growth in his obsessive quest - spanning three continents - to find real-life "NZT-48."

---

## [An antioxidant-rich chemical](https://www.limitlessmindset.com/ALA), that fights stress and a variety of neurodegenerative diseases.

A University of Massachusetts study also demonstrated that it increases cognitive performance in combination with [L-Carnitine](https://www.limitlessmindset.com/nootropic-ingredients/325-alcar), [Alpha-GPC](https://www.limitlessmindset.com/nootropic-ingredients/333-choline), [DHA](https://www.limitlessmindset.com/nootropic-ingredients/338-dha), and [phosphatidylserine](https://www.limitlessmindset.com/nootropic-ingredients/315-phosphatidylserine).

## **Mitochondrial** Antioxidant

![Mitochondria and the Future of Medicine](https://www.limitlessmindset.com/images/Mitochondria_and_the_Future_of_Medicine.jpg)From [Dr. Lee Know's recent book](https://amzn.to/2LlGnPF)

> additional ALA provided by supplements allows it to circulate in a “ free ” state , where it has the ability to function as both a water - and fat - soluble antioxidant . This is unique because most antioxidants are effective in only one area or the other . Vitamin C , for example , is usually restricted to the interior cytosolic ( watery ) compartment of cells , while vitamin E works at the level of the fatty cell membranes . Further , ALA has an important role in the production of glutathione , one of the “ primary ” antioxidants produced directly by the body . Where ALA surpasses other conventional antioxidants is that it is targeted to the mitochondria . Most other antioxidants can’t effectively concentrate at the level of the mitochondrion and so are almost meaningless in their ability to support the most important generator of free radicals .(2596-2603)

## BDNF Biohack

![Boundless book](https://www.limitlessmindset.com/media/reviews/photos/original/f1/d8/4c/the-heartmath-solution-91-1638463084.jpg)It makes the list of BDNF enhancers in Ben Greenfield's [*Boundless*](https://www.limitlessmindset.com/books/955-boundless)...

> Research suggests that ALA increases brain-derived neurotrophic factor, which plays a major role in maintaining neurons and improving learning and memory. (p.139)

## Cold Storage

> ALA is not stable at room temperature for long . What happens is that elevated temperatures cause ALA molecules to polymerize ( link together to form chains ) , and this form doesn’t seem to be absorbable . For this reason , a stabilized R ( + ) ALA product or one that is sold from the fridge ( and stored in the fridge at home ) is best . At the very least , definitely avoid exposing ALA to any sources of heat (2628-2630)

***Downloadable Alpha-Lipoic Acid?***

You may be interested in taking it as an [*infoceutical*](https://www.infopathy.com/en/infoceuticals/cyto-ala?invite=18735093) - a non-pharmacological, side-effect-free version of the drug that takes advantage of the phenomenon of *water memory* - which is imprinted on water via quantum collocation and electromagnetism using this device...

Infocueticals typically have 1/3 or half the effect of the actual medicine being imprinted. If you're skeptical of Infopathy that's understandable, it's a game-changing application of a little-known scientific phenomenon. But I'd urge you to evaluate the scientific evidence (presented in my biohacker review) that *downloadable medicine is no longer science fiction...*

## **Cofactors**

Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance. 

### Nootropic Ingredients

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