---
title: "Pyrroloquinoline Quinone: Mitochondrial support (from space?) - Limitless Mindset"
description: "{loadposition ArticleHeader} On the extraterrestrial origin of PQQ From Dr. Lee Know's recent book From an evolutionary perspective , current evidence suggests PQQ is a component of interstellar dust , and since it’s been postulated that strong redox catalysts were required to trigger the earliest chemical evolutionary steps , the extraterrestrial origin of PQQ raises the question of its evolutionary importance to simpler life forms . This theory is especially interesting when you consider PQQ’s ..."
author: Jonathan Roseland
url: https://www.limitlessmindset.com/nootropic-ingredients/904-pyrroloquinoline-quinone
---

# Pyrroloquinoline Quinone (PQQ)

[![Pyrroloquinoline Quinone (PQQ)](https://www.limitlessmindset.com/data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)](https://www.limitlessmindset.com/media/reviews/photos/original/b4/b7/4b/pyrroloquinoline-quinone-40-1529479743.webp "Pyrroloquinoline Quinone (PQQ)")

Ⓒ By **Jonathan Roseland**

Applied Neuroscience Strategist, K-Selected Biohacker, Tantric husband, Promethean peaceful parent, Adventuring philosopher, Raconteur, and Author. He spent +14 years researching the intersection of human performance enhancement and advanced personal growth in his obsessive quest - spanning three continents - to find real-life "NZT-48."

---

## On the *extraterrestrial origin* of [**PQQ**](https://www.limitlessmindset.com/PQQ)

From [Dr. Lee Know's recent book](https://amzn.to/2LlGnPF)

> From an evolutionary perspective , current evidence suggests PQQ is a component of interstellar dust , and since it’s been postulated that strong redox catalysts were required to trigger the earliest chemical evolutionary steps , the extraterrestrial origin of PQQ raises the question of its evolutionary importance to simpler life forms . This theory is especially interesting when you consider PQQ’s wide range of chemical properties , such as a redox catalyst and the ability to modify amino acids ( e.g . , oxidative deamination reactions ) . Could PQQ be our common point of origin with life in other areas of the galaxy ? (2290-2294)

## Stimulates the Growth of Mitochondria

![Mitochondria and the Future of Medicine](https://www.limitlessmindset.com/images/Mitochondria_and_the_Future_of_Medicine.jpg)

> Traditionally , it was believed that generating new mitochondria ( mitochondrial biogenesis ) could only occur as a result of strenuous exercise or extreme calorie restriction , which is why research on PQQ ( pyrroloquinoline quinone ) is so exciting . Early in 2010 , researchers found PQQ not only protected mitochondria from oxidative damage , it also stimulated the growth of new mitochondria ! (2274-2277)

## PQQ as a **Nootropic**

> Related to this is cognitive function . As we discussed , the brain uses an incredible amount of energy , and it is utterly dependent on the mitochondria for fuel . A double - blind , randomized , placebo - controlled human clinical trial found that **20 milligrams** of oral PQQ taken daily improved short - term memory , attention and concentration , information identification , and processing ability in healthy adults . Effects were greatly enhanced with the addition of CoQ10 supplementation , which makes sense because Complex I transfers its electrons to CoQ10 in the ETC .(2334-2338)

## Vs **Cancer**

> PQQ can also reduce cancer risk by mechanisms separate from mitochondrial biogenesis . For example , PQQ has been shown to affect the activity of ras ( a gene that can potentially cause cancers ) (2304-2306)

## A **B Vitamin**

> In 2003 , Japanese scientists made a significant announcement in the prestigious journal Nature : They had discovered direct molecular evidence that PQQ was in fact a previously unidentified B vitamin . A vitamin , by definition , is a compound that human bodies can’t make ( we must get it from dietary sources ) and is an absolute necessity to carry out at least one essential biochemical function . (2315-2318)

***Downloadable PQQ?***

You may be interested in taking it as an [*infoceutical*](https://www.infopathy.com/en/infoceuticals/pyrroloquinoline-quinone-pqq?invite=18735093) - a non-pharmacological, side-effect-free version of the supplement that takes advantage of the phenomenon of *water memory* - which is imprinted on water via quantum collocation and electromagnetism using this device...

Infocueticals typically have 1/3 or half the effect of the actual medicine being imprinted. If you're skeptical of Infopathy that's understandable, it's a game-changing application of a little-known scientific phenomenon. But I'd urge you to evaluate the scientific evidence (presented in my biohacker review) that *downloadable medicine is no longer science fiction...*

## Mechanism of Action

![Boundless book](https://www.limitlessmindset.com/media/reviews/photos/original/f1/d8/4c/the-heartmath-solution-91-1638463084.jpg) Ben Greenfield writes in his anti-aging manifesto, [*Boundless*](https://www.limitlessmindset.com/books/955-boundless)...

> Pyrroloquinoline quinone (PQQ) is an antioxidant that’s involved in redox reactions, which change the oxidation states of atoms, in living organisms ranging from bacteria to human beings. More than 175 published studies have shown that it has wide-ranging benefits for memory, general cognition, mood, and mental processing power, making it a popular ingredient in many nootropics. PQQ’s benefits also include increased mitochondrial density, defense against oxidative stress, improved learning and memory ability, and reduced inflammation.

## Dietary Souce: **Chocolate**

> More research should be done to clarify PQQ’s contribution to the health benefits of chocolate , but in the meantime , moderate consumption of dark chocolate would seem to be a great way to treat yourself (2347-2348)

## **Cofactors**

> Using PQQ in combination with [**CoQ10**](https://www.limitlessmindset.com/CoQ10) seems to synergistically increase their potency, so I recommend taking a combination supplement that includes both... ([p.965](https://www.limitlessmindset.com/#Boundless))

 

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