---
title: The Gut-Brain Connection with Gabe Dough of Good Bru - Limitless Mindset
description: "The gut-brain connection is deeper, weirder, and far more literal than we ever imagined. I interview Gabe Dough, the founder of Good Bru. His product combines prebiotics with a resilient probiotic strain, BC30, which I've been using."
author: Jonathan Roseland
url: https://www.limitlessmindset.com/podcast/1682-good-bru
---

# The Gut-Brain Connection with Gabe Dough of Good Bru

Ⓒ By **Jonathan Roseland**

Applied Neuroscience Strategist, K-Selected Biohacker, Tantric husband, Promethean peaceful parent, Adventuring philosopher, Raconteur, and Author. He spent +14 years researching the intersection of human performance enhancement and advanced personal growth in his obsessive quest - spanning three continents - to find real-life "NZT-48."

---

[Subscribe to the Limitless Podcast](https://www.limitlessmindset.com/LM-Podcast) To Listen on the Go

The gut-brain connection is deeper, weirder, and far more literal than we ever imagined. For years, we’ve been told that our 'gut feeling' is just a metaphor for intuition. But recent science suggests that your gut is actually a 'second brain'—a complex neural network of 100 million neurons that can operate entirely on its own, independent of the one in your skull.
We aren't just talking about digestion; we’re talking about a bidirectional superhighway where bacteria in your colon produce up to 90% of your body’s serotonin and significantly influence your levels of GABA, the primary neurotransmitter for calm. Essentially, the 'critters' in your gut might be the master puppeteers of your mood, your sleep, and even your cognitive clarity.
But as the market for 'gut health' explodes, the gap between marketing claims and clinical reality is widening. I interview **Gabe Dough**, the founder of[**Good Bru**](https://www.limitlessmindset.com/Good-Bru). 

![Gabe Dough](https://www.limitlessmindset.com/media/reviews/photos/original/a4/c1/44/good-bru-34-1768203751.webp)

His product bridges that gap using a specific combination of prebiotics and a resilient probiotic strain known as BC30, which I've been using...

![](https://www.limitlessmindset.com/media/reviews/photos/original/8d/99/fc/good-bru-40-1768120236.webp)

## **Mentioned** here

**Organic Agave Inulin** - A prebiotic fiber validated by [19 human scientific papers](https://pubmed.ncbi.nlm.nih.gov/?term=Agave+Inulin&filter=hum_ani.humans)

**Bacillus coagulans GBI-30 (BC30)** - a super-probiotic validated by [+50 human clinical studies](https://pubmed.ncbi.nlm.nih.gov/?term=%28Bacillus+coagulans%5BTitle%2FAbstract%5D%29+OR+%28BC30%5BTitle%2FAbstract%5D%29&filter=pubt.clinicaltrial&filter=hum_ani.humans)

**Lactobacillus Reuteri** (pitched by a [65-year-old sexpert](https://podcasts.apple.com/us/podcast/206-optimizing-bedroom-performance-for-men-women-with/id1520485498?i=1000640130980)) for boosting Oxytocin

**DIY your own probiotic yogurt** - Get a [yogurt maker](https://amzn.to/4qfN3lw) for culturing

**Probiotics for PICOS**: [Effects of Synbiotic-Containing Bacillus coagulans (GBI-30) on the Cardiovascular Status of Patients With Polycystic Ovary Syndrome: A Triple-blinded, Randomized, Placebo-controlled Study.](https://pubmed.ncbi.nlm.nih.gov/37640616/)

**My research on fertility optimization**: [Decode Your Genome with Personal Genotyping for Precision Fertility Optimization](https://www.limitlessmindset.com/blog/134-fertility-optimization-personal-genotyping)

**Self-quantification**: [personal genomics](https://www.limitlessmindset.com/Sequencing) and [gut microbiome testing](https://www.limitlessmindset.com/viome)

**Probiotics for protein absorption**: [Probiotic Bacillus coagulans GBI-30, 6086 Improves Protein Absorption and Utilization.](https://pubmed.ncbi.nlm.nih.gov/29196920/)

**Probiotics for children**: [Bacillus coagulans GBI-30, 6068 decreases upper respiratory and gastrointestinal tract symptoms in healthy Mexican school-aged children by modulating immune-related proteins.](https://pubmed.ncbi.nlm.nih.gov/31554075/)

**Probiotics for Psoriasis**: [Transforming Psoriasis Care: Probiotics and Prebiotics as Novel Therapeutic Approaches](https://pubmed.ncbi.nlm.nih.gov/37446403/) out of Cluj-Napoca, Romania ([where I once spent a couple of weeks](https://www.limitlessmindset.com/index.php?option=com_content&view=article&id=769:bucharest&catid=8:blog-articles&Itemid=169))

**Probiotics for bone loss**: [Bacillus coagulans ameliorates inflammatory bone loss in post-menopausal osteoporosis via modulating the "Gut-Immune-Bone" axis](https://pubmed.ncbi.nlm.nih.gov/40275534/)

**Probiotics for irritable bowel syndrome**: [Efficacy and safety of Bacillus coagulans LBSC in irritable bowel syndrome: A prospective, interventional, randomized, double-blind, placebo-controlled clinical study [CONSORT Compliant]](https://pubmed.ncbi.nlm.nih.gov/33545934/)

**Weird gut science**: [Personality transplant via gut microbes](https://www.mdpi.com/2076-2607/10/5/1054#:~:text=Overall%2C%20these%20data%20demonstrated%20that,transplantation%20(FMT)%3B%20Meriones%20unguiculatus), [microbial hijacking of craving control](https://chriskresser.com/do-gut-microbes-control-your-food-cravings/#:~:text=Individual%20genera%20of%20bacteria%20have,fiber%20(7%2C%208).), and the [brain as "PR department" for the gut](https://neuroscience.ubc.ca/our-second-brain-more-than-a-gut-feeling/#:~:text=In%20fact%2C%2090%25%20of%20the,can%20massively%20influence%20the%20brain.) 

**Probiotic cofactors**: [HMB](https://www.limitlessmindset.com/index.php?option=com_content&view=article&id=1815:pure-hmb&catid=78:nootropics-anti-aging&Itemid=233) and [NMN](https://www.limitlessmindset.com/index.php?option=com_content&view=article&id=562:nmn&catid=65:nootropic-ingredients&Itemid=244) for boosting NAD+ (potentially)

### *"Getting your gut health right gives you the right to architect your personality and therefore your reality..."*

Is how I concluded the interview with Gabe, and I like what [Good Bru](https://www.limitlessmindset.com/Good-Bru) is about, so I've included them as a [Limitless Mindset Secret Society](https://www.limitlessmindset.com/index.php?option=com_content&view=article&id=25:limitless-mindset-secret-society&catid=8:blog-articles&Itemid=397) recommended vendor. **Pick up over $300 worth of product from them (or mix and match with other Secret Society vendors) and get a helpful free Biohacking consultation with me**.

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#### My discussion with Gabe inspired this song about probiotics:* "Second Mind Mariachi"*

## **Finally**...

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