159 results - showing 41 - 50
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Do piracetam-like compounds act centrally via peripheral mechanisms?
The pharmacological mechanism of action of the piracetam-like nootropics is still obscure. Their unique feature is that they exert distinct effects on memory, but show hardly any biochemical activity and are practically devoid of toxic effects. Our results indicate that the memory-enhancing action of these substances is dependent on the presence of the adrenals, suggesting that their central effects...
Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial.
OBJECTIVE: The objective of this study was to investigate the effectiveness of Bacopa monnieri Linn. for improvement of memory performance in healthy older persons.
Does excessive memory load attenuate activation in the prefrontal cortex? Load-dependent processing in single and dual tasks: functional magnetic resonance imaging study.
Abstract: Functional magnetic resonance imaging was used to investigate the relationship between cortical activation and memory load in dual tasks.
The frequency of working from home has been rising rapidly in the US, with over 10% of the workforce now regularly work from home. But there is skepticism over the effectiveness of this, highlighted by phrases like "shirking from home". We report the results of the first randomized experiment on home-working in a 13,000 employee NASDAQ listed Chinese firm....
Effect of modafinil on learning and task-related brain activity
Abstract Methamphetamine (MA)-dependent individuals exhibit deficits in cognition and prefrontal cortical function. Therefore, medications that improve cognition in these subjects may improve the success of therapy for their addiction, especially when cognitive behavioral therapies are used. Modafinil has been shown to improve cognitive performance in neuropsychiatric patients and healthy volunteers. We therefore conducted a randomized, double-blind, placebo-controlled, cross-over study,...
Effect of supplementation with polyunsaturated fatty acids and micronutrients on learning and behavior problems associated with child ADHD.
AbstractMETHODS:Various developmental problems including attention-deficit/hyperactivity disorder (ADHD) have been linked to biological deficiencies in polyunsaturated fatty acids (PUFAs). Additionally, there is evidence that symptoms may be reduced with PUFA supplementation. This study investigated effects of supplementation with PUFAs on symptoms typically associated with ADHD. Because nutrients work synergistically, additional effects of micronutrient supplementation were also investigated. A total of...
Effect of the nootropic drug oxiracetam on field potentials of hippocampal slices
1. The effect of the nootropic drug oxiracetam on hippocampal neurotransmission was investigated in the CA1 region of the rat hippocampal slice in vitro by use of extracellular recordings. 2 Superfusion of oxiracetam (0.1–100 μm) produced a concentration-dependent, wash-resistant (>90 min), increase in initial slope and amplitude of the dendritic field excitatory postsynaptic potential (e.p.s.p.). This increase was maximal...
Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients.
Abstract Hypothesis. Withania somnifera is an herb with antioxidant, anti-inflammatory, anticancer, antistress, and adaptogenic properties. Previous studies have shown its antistress effects in animals. Traditional Indian medicine has used it for centuries to alleviate fatigue and improve general well-being. METHODS: This is an open-label prospective nonrandomized comparative...
Effectiveness of emWave biofeedback in improving heart rate variability reactivity to and recovery from stress.
Abstract The current study examined the efficacy of heart rate variability (HRV) biofeedback using emWave, a publicly available biofeedback device, to determine whether training affected physiological tone and stress responses. Twenty-seven individuals aged 18-30 years were randomized to a treatment or no-treatment control group. Treatment participants underwent 4-8 sessions of emWave intervention, and all participants attended pre-treatment...
Effects of combined treatment with heavy metals and Piracetam on learning and memory
The effects of the nootropie drugs Piracetam (Pir) and Pramiracetam (Pram) were evaluated on recognition-memory of rats in a new one-trial test. This test is based on spontaneous exploratory activity and does not involve rule learning or reinforcement. Recognition is measured by the time spent by rats in exploring two different objects, one familiar (the sample), the...
159 results - showing 41 - 50
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