Centrophenoxine by Pure Nootropics

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Centrophenoxine by Pure Nootropics

Centrophenoxine is a cholinergic compound which is a derivative of Dimethylaminoethanol (DMAE) and pCA (para-chlorophenoxyacetic acid) (1). As a cholinergic, it increases levels of acetylcholine in the brain.

May increase alertness and support memory (ref)*
May increase concentration and focus (ref)*

Centrophenoxine is a subject of interest in the medical community but thus far, the amount of clinical trials in humans is not plentiful. Some of these human studies are referenced above.

The following references are examples of dynamics associated with Centrophenoxine through the animal model and may not be representative of the effects in the human body:

Promotes antioxidant activity (ref)(ref)*
Supports information recall in elderly animal subjects (ref)*
May decrease lipofuscin (pigments related to aging) (ref)*
Supports RNA synthesis (ref)*


Centrophenoxine is prescribed in some countries under the brand name “Lucidril” to help combat Alzheimer’s. It is synthesized from DMAE. DMAE is a natural chemical that has been shown to improve areas of cognition and mood. DMAE’s exact method of action is slightly disputed. Some see it as a precursor to Acetylcholine but others contest this as choline molecules broken down from DMAE are not believed to cross the blood-brain-barrier efficiently.

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Centrophenoxine by Pure Nootropics

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