By Jonathan Roseland

I'm not a doctor, medical professional, or trained therapist. I'm a researcher and pragmatic biohacking practitioner exercising free speech to share evidence as I find it. I make no claims. Please practice skepticism and rational critical thinkingYou should consult a professional about any serious decisions that you might make about your health. Affiliate links in this article support Limitless Mindset - spend over $150 and you'll be eligible to join the Limitless Mindset Secret Society.

The Secret Weapon of Formidable "Lab Rats"

Is your “Lab Rat” ballin’ on a budget? MK-677 (also called Ibutamoren) is a game-changing and low-risk growth hormone alternative that’s a lot easier on your furry friend’s bankroll...

Disclaimer: This is a legal “NOT for human consumption” research chemical - if you don’t understand what that means, don’t use it.

Here we’ll summarize the recent findings from the human studies done and insights from some very sapient “Lab Rats” around the web...

Human growth hormone molecule

Human growth hormone is a tremendous tool for unlocking greatness in nearly every dimension of human performance, but it comes at a price, between $200 - $1250 monthly. For non-millionaires, MK-677, an oral Ghrelin secretagogue, is the growth hormone alternative, which will give you a lot of bang for your buck, costing $50 - $65 monthly.
Other than the stark economic advantage, what makes MK-677 appealing to me, a guy who normally shies away from “research chemicals” is that it doesn’t replace hormones resulting in your body producing FEWER hormones. It just feeds your pituitary gland the fuel it needs to naturally produce MORE human growth hormone.

 Scientific Research


It’s a relatively well-understood “research chemical,” on Pubmed you can find 100 scientific papers about it and nearly twenty clinical trials. Unlike some research chemicals, the papers and studies on it are not isolated to a single university, research group, or country. It was initially researched by Merck, they published an optimistic paper back in the ’90s concluding...

[Growth hormone] secretagogues could provide a well-tolerated clinical approach for treating or preventing sarcopenia, and perhaps, even forestall the inevitability of age-associated decline in function and independence. Such efficacy would have a great social impact.

Some other notable findings...

  • The most recent human clinical trial was completed in 2018 at the University of Virginia and found that it increases serum insulin-like growth factor 1 in hemodialysis patients. Hemodialysis is a condition of poisoned blood resulting from kidney dysfunction.
  • Another study from the same university found it effective for weight loss over 12 months, significantly increased fat-free mass, and was generally well tolerated.
  • A Chilean study gave it to growth hormone-deficient children (I think that’s what I was as a little guy!) and noted no adverse effects, it was safe even for children.
  • Published science recognizes it as a promising anti-aging invention. Although, according to Merck's research, it doesn't have an effect counteracting cognitive decline in Alzheimer’s patients.
  • The most recent paper published surmised that it would have an antiviral activity against Ebola.

What to expect from MK-677...

  • Muscle growth - Derrick of More Plates More Dates advises that on it, one can expect to put on “seven to ten pounds of muscle in the first week.” That seems a bit fanciful to me, but bodybuilders agree, you can put on muscle fast with this stuff!
  • Muscle Preservation - If Coronavirus quarantine season has your favorite gym’s doors locked, you can maintain your musculature with MK-677. Some bodybuilders report that they stopped going to the gym altogether for months yet maintained their muscles just by taking MK-677.
  • Healing - In the anecdotal corpus of evidence, you’ll find a lot of accounts of it seeming to help with the healing of injuries, strains, and sprains rapidly. This makes sense as the uptick in growth hormone enhances the body’s capacity to heal itself.
  • Increases bone density - In human studies, it resulted in healthier, less fragile bones. Not only is this good news for elderly folks worried about slipping and breaking a hip while taking a shower, but it also mitigates the risk of workout injury.
  • Cognitive enhancer - According to my friend, Errol Greene, it’s quite a powerful Nootropic. It just gives you loads of energy and motivation.
  • Boosts metabolism and burns fat - It kicks your metabolism into high gear. If you’re getting a lot of exercise while on-cycle you can anticipate shedding a lot of fat if you need to.
  • Super sleep - More about this below...

 Side Effects

There are three notable effects to consider...

  • Hunger “pains” - It will dramatically increase your appetite! Ghrelin is the hunger hormone so expect to be hungry. You’re going to be eating a lot, so you need to really GO HARD in the gym to burn all those calories. The best way to avoid being a ferocious snacker is to take it before bed so it works on your metabolism while you’re sleeping.
  • Insulin Resistance - Something like MK-677 is going to have a long-term effect of desensitizing your Insulin receptors. For this reason, you would want to cycle it and use something alongside something that will improve Insulin sensitivity like Resveratrol (or better, Pterostilbene).
  • Sleepiness - Some report that it makes them drowsy or fatigued in the mornings, while others don’t.

 Sleep Hack

Sleep Hack

Expect dramatically deeper sleep. You’ll get 10-12 hours of restoration/repair sleep. Amazing sleep is one of the secret weapons of world-class high performers. Many report that this profound sleep gives them amazing energy and motivation during the day. But for some, the deep sleep makes them sluggish during the day. You’ll have to try it yourself to see how you respond and experiment with taking it at different times...

  • Directly before bed - this seems to be the most popular
  • Several hours before bed
  • In the morning

For nocturnal adventurers, MK-677 before bed results in intensely vivid dreams.

 Vanity Hack


Anecdotally, it’s a “research chemical” for the vain. All the guys vlogging on YouTube about it have pretty great hair. Boosting IGF-1 promotes hair growth and health, it also results in clearer, more vibrant skin. It tightens skin, in Ayn Rand’s novels, the protagonists are described as having very tight, angular faces. It’s undebatable, symmetry is beautiful and evokes archetypes of heroism.

 To SARM or not to SARM?

Growth, hormone diagram

To clarify, it’s not a SARM, it’s a Secretagogue - meaning it’s a precursor chemical that stimulates the secretion of growth hormone.

  • It’s non-steroidal.
  • Unlike testosterone replacement therapy, you don’t need to worry about it suppressing natural testosterone.

 Mechanism of Action

MK-677 molecule

As a growth hormone-releasing peptide, it works via several different actions...

  • Ghrelin receptor agonist.
  • Growth Hormone - It gives you 60% - 70% more growth hormone. It helps your pituitary gland to produce its own growth hormone.
  • Increases serum IGF-1 levels.


Errol Greene, who I interviewed first turned me onto MK-677, describes it as his own personal NZT-48 “Limitless Drug”...

  • Apparently, the MK-677 suspension is not good, reviewers advise that this can be easily overcome with orange juice.
  • Expect subtly tingly fingers and hands.

What guys are saying about it...
Awesome - Jose F.

Lab rat gained about 10 pounds in first weeks.

First Time Using MK677 - John C.

My “lab rat” had a pulled muscle for about 8 weeks, causing me to remove pullups and bicep workouts from its weekly regiment. On my second week of dosing my lab rat MK677, the pain was almost completely gone.

Works great! - Mark

I ordered this product together with RAD140 and this stuff works! Just nearly done my first cycle. I’ll be ordering another.

Mk677 of the gods - Zachary G.

Bought the powder and have gotten some of the best sleep of my life. Fully recommend. Thanks Narrow

The real deal! - Ross

Based on the smell, appearance, and experimental results, I can confidently say that this Mk-677 powder is legit! It gives your lab rat a noticeable strength boost with little to no side effects.


Because of the insulin desensitization effect, you would want to use Resveratrol (or even or better, Pterostilbene) which have an insulin sensitization effect.

Some other suggested cofactors...

 Usage & Dosage

  • 20 - 30 milligrams daily.
  • It does not need to be refrigerated.
  • Taking it before bed is typical.
  • Cycle it, take it for at least a month, a typical cycle is 6 months. After a cycle, take a month off.

Where to buy MK-677

MK-677 can be taken powdered, as a suspension, and Swiss Chems offers it capsuled - the most convenient form.


  • Suspension - This 30-milliliter bottle contains 25 milligrams of MK-677 per milliliter. It comes with a syringe, you’re not going to be injecting it. Just use the syringe for precision measurement.
  • Powdered - If you don’t mind consuming it as a powder, this is the most economical option. This 1000-milligram supply would last over a month even if you were taking a higher dose every day of 30-milligrams. At a moderate dosage of 20 milligrams daily, this would last you 50 days.
  • Capsuled - Sixty 10-milligram capsules, at a moderate dosage of 20 milligrams daily, this is a month’s supply.

Is MK-677 in a legal grey zone?

Research chemicals are legal to possess and sell, but you have no one to complain to if you consume them and have a bad experience because they are “Not for Human Consumption”. But if you live in a particularly persnickety state it may be wise to check your local laws, I’m sure it’s banned somewhere.

Like SARMs and other research chemicals, you need to be very wary of scams and frauds.

Many online sources are unwittingly selling bunk MK-677 because they will buy from a Chinese wholesaler that will ship an initial supply of pure stuff but subsequent batches will be adulterated, expired, or simply fake. The bodybuilding research chemical space is so rife with fraudulent stuff that, humorously, some male bodybuilders use pregnancy tests to figure out if they are using the real stuff. Luckily, it’s pretty easy to ensure that you’re getting legit stuff; demand to see a valid certificate of analysis done by an accredited American spectroscopy lab, it should look like this...

MK-677 COARecent COA for MK-677

Downloadable MK-677?

You may be interested in taking it as an infoceutical - a non-pharmacological, side-effect-free version of the supplement that takes advantage of the phenomenon of water memory - which is imprinted on water via quantum collocation and electromagnetism using this device...

Infocueticals typically have 1/3 or half the effect of the actual medicine being imprinted. If you're skeptical of Infopathy that's understandable, it's a game-changing application of a little-known scientific phenomenon. But I'd urge you to evaluate the scientific evidence (presented in my biohacker review) that downloadable medicine is no longer science fiction...

 Bottom Line...

MK-677 seems to be a real-life cheat code for human growth, I would try it in moderation if I could devote serious time weekly to exercise, sleep, and stuffing my face. If I were going to go on a 6-month MK-677 cycle I would get my insulin sensitivity tested every couple of months, the insulin resistance is the one side effect that concerns me.
Currently, I’m Corona-tined and my gym is closed, if I had a 1-year long-term food supply instead of a 2-month supply and a decent home gym, I would totally go on MK-677.

Originally published on


MK-677 Growth, hormone mechanism, diagram


MK-677 ? The Secret Weapon of Formidable "Lab Rats"

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